Gel imaging 2D Gel Image Analysis Software

Gel imaging 2D Gel Image Analysis Software

Dymension is revolutionary software that can analyse a typical 2D gel image rapidly. It features novel algorithms for background subtraction, noise filtering, precise alignment, spot detection, rapid matching and reduced image editing time. Using its powerful spot detection algorithm, Dymension instantly locates and analyses protein spots. With Dymension, the entire analysis process from background correction to spot matching results and reporting takes minutes, making this the fastest 2D gel analysis package currently available.

Dymension is available in three versions, and upgrading between the packages is simple.

Applications & Benefits
Dymension 1 -
analysis of single 2D gels
Dymension 1 is ideal for users looking for software to analyse spots between samples containing one 2D gel only. It offers a range of automatic image correction features and methods of resolving and analysing spots on single gels. The software can be easily upgraded to Dymension 2 or 3 if the proteomics needs of the laboratory change.
Dymension 2 -
rapid analysis of multiple 2D gel sets
Dymension 2 has all the features of Dymension 1 but has the added ability to detect and compare protein spot maps in samples containing replicate gels. The software offers many background correction and noise filtering features including a SYPRO® Ruby filter, which can detect and automatically remove spots caused by SYPRO® Ruby crystals adhering to the gel, thus saving users valuable time editing their image.

Dymension 2 is suitable for users that need to determine the amount of protein present before and after drug or protein induction treatments. The software automatically detects and assigns statistical confidence to each and every difference in spot normalised volume, thus accurately highlighting proteins of specific interest. The results of the analysis are displayed as a dynamically linked table, 3D spot profile, bar chart, correlation and scatter plot, which make it easy to compare many expression profiles simultaneously and therefore accurately pick proteins suitable for further analysis.
Dymension 3 -
quick and easy analysis of all 2D gel applications
Dymension 3 is exciting software, which has all the functionality of Dymension 2 so can be used to analyse samples containing replicate gels. Dymension 3 has the additional capability to analyse multi-stained fluorescent gel images stained with up to three contrasting labels, eg, Cy™2, Cy™3 and Cy™5. This feature allows users to analyse multiple sets of any type of 2D protein gel, regardless of how it was stained, using only one software package.
Dymension 1 -
analysis of single 2D gels
Dymension 1 is ideal for users looking for software to analyse spots between samples containing one 2D gel only. It offers a range of automatic image correction features and methods of resolving and analysing spots on single gels. The software can be easily upgraded to Dymension 2 or 3 if the proteomics needs of the laboratory change.

Ordering Information

Software for 2D Gels

Dymension 2 softwareDYM-22.700,00 €
Dymension 3 softwareDYM-33.750,00 €

Dr. Cagdas Tazearslan, Research Associate
Albert Einstein College of Medicine, New York, USA

We installed a Dyversity imaging system in 2008 because we needed to accurately detect small amounts of proteins associated with the human aging process. The Dyversity has been very easy to use as the training and the technical support we have had from Syngene have been exceptional.

With the system, we have been able to rapidly generate reproducible data which let us measure phosphorylation levels of different signal transduction molecules in insulin-like-growth factor1 pathway so the quantification and analysis capabilities of the Dyversity are exactly right for our work.

Dr Sonali Patil, Scientist
Burzynski Research Institute, Texas, USA

Since 2007, we have been using the Dyversity 2D image analysis system to analyze proteins associated with brain tumors on chemiluminescent Westerns and have detected and quantified bands which we haven't been able to see using other image analyzers. We also use Dyversity with Dymension 2D analysis software to quantify protein spots on 2D gels because the two together make this complicated analysis straightforward.

The technical support we have had from Syngene is excellent. They have taught us how to use the software efficiently and have always been prompt to respond to all our queries with helpful suggestions. I would go so far as to say we have never had such great support from any other company and I would recommend a Dyversity and Dymension to anyone thinking of doing 2D gel work.

Dr. Jane Gray, Senior Scientific Officer
Cancer Research UK's Cambridge Research Institute, Li Ka Shing Centre, Cambridge, UK

Our Dyversity system is used by a number of different research groups to image chemiluminescent and fluorescent Westerns, as well as DNA and protein gels of a variety of cancers. The service we have had from Syngene is excellent, as they trained us to get the best out of the Dyversity's software and even helped us with a more unusual fluorescence application.

We have used different imagers in the past and they were so complicated to set up that it is great to use the Dyversity system where the software is intuitive. Using the system we have obtained perfect chemiluminescent blot results, without having to stand over them or become a camera expert, which makes Dyversity the perfect imager for our research.

Professor Beat Riederer
Centre for Psychiatric Neurosciences, Department of Psychiatry, University of Lausanne, Switzerland

In 2007 we started using the Syngene Dyversity system to speed up the imaging of our DIGE* gels. We label our proteins with fluorescent dyes to detect differences in the protein composition and use Coomassie Blue stained gels to identify specific proteins by mass spectrometry. We utilise the Dyversity system, because it offers the possibility to use several wavelengths to detect fluorescent emissions of three or more labeled protein mixtures separated on the same two-dimensional electrophoresis gel.

*DIGE is differential 2D gel electrophoresis

Dr. Victor M.Bautista de Lucio, Professor Researcher
Institute of Ophthalmology Fundacion Conde de Valenciana, Mexico

We chose a Dyversity system in 2010 after reviewing two other image analyzers because it is reasonably priced and includes filters and software that are useful for analyzing our 2D gels. We are using Dyversity to detect proteins extracted from the tears of patients with different eye diseases and with this system, we can easily capture high-quality images of our gels and blots, which we analyze using Syngene's GeneTools and Dymension software.

The service we have had from Syngene has been excellent because we always receive support whenever we need it. Using Dyversity has helped us to establish good proteomic profiles in several ocular diseases and we have written three papers using data generated by the Dyversity, so we are very happy with our Dyversity system.

Applications & Benefits
Ordering Information

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