Cytogenetics is a branch of genetics,
studying the structure and function of the cell


Cytogenetics analyses the number and structure of human and animal chromosomes. Changes that affect the number or structure of the chromosomes can cause problems with growth, development, and how the body functions.

Structural changes in chromosomes can lead to birth defects, syndromes or even cancer. Chromosomal changes may have no effect on a person's health.

Cytogenetic analyses are commonly performed during pregnancy to determine if there is an indication that the fetus is at risk for common aneuplodies (syndromes caused by having extra or missing chromosomes), syndromes caused by structural abnormalities (like unbalanced translocations or inversions), or to determine if extra or missing genetic material is present.

The diagnosis and treatment of several leukemias and lymphomas, as well as some solid tumors, depends today on cytogenetic analysis of specific chromosomal aberrations that are consistently observed in these particular cancers.

The analysis of chromosomes in human development and disease is accomplished through classical cytogenetic procedures, such as G-banding, combined with advanced molecular techniques such as FISH and genomic microarray analysis (CGH) as well as next generation sequencing (NGS).

Product of the month
MetaPrep Automatic Robotic Slide Preparation Instrument
MetaPrep Automatic Robotic Slide Preparation Instrument
Achieving a high mitotic index and consistent spreading when preparing slides can be a real challenge for cytogenetic laboratories. The correct climatic conditions and concentration of the suspensions are all important to produce consistent results. The MetaPrep system allows the cytogeneticist... more

Products for Karyotyping

Karyotyping is a technique where the chromosomes from one cell are visualized under a microscope to investigate the total number and structure of the chromosomes. Cells are obtained and cultured from an individual and are analysed during metaphase, a stage in cell division when...
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Cell Harvester

Automatic metaphase harvesting is a technique that may be applied all common sample types that are cultured for subsequent cytogenetic analysis. Typically, automatic metaphase harvesting may offer several attractions to a typical cytogenetics laboratory, where the deployment of...
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MultiPrep Genie 205™
Cytogenetic In Situ Culture Harvester

MultiPrep Genie 205™<br>Cytogenetic In Situ Culture Harvester
MultiPrep Genie is specifically designed for cytogeneticists carrying out in situ coverslip harvesting and offers true 'walk away' robotic harvesting, not only improving productivity and permitting faster turn around times, but freeing time for the technicians to perform skilled...
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MultiPrep CellSprint™ Automated Cytogenetic Suspension Culture Harvester

MultiPrep CellSprint™ Automated Cytogenetic Suspension Culture HarvesterMultiprep CellSprint has been designed in collaboration with leading cytogenetics laboratories as a true walk-away automation solution designed to relieve suspension culture harvesting workload pressures in busy cytogenetics laboratories.The unique robotic pick and place arm...
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MetaSlide Prep

MetaSlide PrepThe MetaPrep system allows the cytogeneticist full control over climate conditions and cell density for reliable and repeatable slide preparations. It accomplishes this by performing the slide dropping in a nested chamber with optimal airflow at the correct temperature and...
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ProCell Reagents

The ProCell cytogenetics reagents range is designed to improve culture failure rates, mitotic index, metaphase spreading, banding resolution and overall quality of bone marrow, lymphoma, solid tumour, blood, CVS and Amniocentesis samples for cytogenetic analysis.
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Products for CGH

Array CGH is a technology that allows detection of chromosome imbalances that are too small to be detected by microscope. Smaller alterations, often called sub microscopic alterations can still disrupt growth and development. These very small changes are called micro deletions...
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Array Processing

Starting with DNA or RNA derived from different sources, specialized instruments work together to perform all labeling, hybridization and post-hybridization microarray processing steps; producing consistently high quality arrays ready for scanning. We offer the relevant...
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NoZone Workspaces

NoZone WorkspacesMaintains Ozone Levels Below 5 ppb Typical day time ozone levels found in most laboratories can destroy Cy5 and other fluorescent dyes used with microarray samples. Studies show that ozone levels as low as 20 ppb can negatively effect array data. The NoZone Workspace was...
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Microarray Ovens

Microarray OvensSeries 700 Microarray Ovens provide heating and bubble-mixing of target/probe solutions within microarray hybridization chambers including those supplied by Affymetrix and Agilent. The Model 777 Microarray Oven provides rotational mixing to 80 RPM for Affymetrix GeneChips, and...
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Little Dipper Processors for Array Work

Little Dipper Processors for Array WorkA SciGene Little Dipper Microarray Processor is a programmable, robotic instrument that automates the various post-hybridization processing steps used with microarrays and FISH. The Little Dipper instrument improves data quality by eliminating sample handling and by...
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Products for FISH

Fluorescence in situ hybridization (FISH) detects the presence, copy numbers and/or location of a DNA sequence within a set of metaphase chromosomes or an interphase nucleus. It is an important molecular cytogenetic technique widely used in diagnosing various genetic disorders...
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Hybridization Incubators

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CytoBrite Duo Slide Incubation System

CytoBrite Duo Slide Incubation SystemDual temperature slide heating instrument with superior temperature control for FISH/ISH applications. Two independently controlled heat blocks each hold a removable 6-slide tray. Trays reduce handling from assay setup through hybridization and can be moved between heat blocks...
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CytoBrite Slide Incubation System

CytoBrite Slide Incubation SystemProgrammable system with superior temperature control for performing FISH/ISH hybridization protocols on 1 to 12 slides. Uses rapid Peltier heating and cooling to process FFPE, bone marrow, cell lines and other samples with FISH probes from Abbott, Agilent, Cymogen and Cytocell....
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CytoBrite Slide Oven

CytoBrite Slide OvenHigh capacity convection oven with superior temperature control for performing extended or overnight probe denaturation of up to 60 FISH/ISH slides. Slides are uniformly heated to &pusmn; 0.5°C from set point. Up to ten 6-slide trays are easily loaded into five sliding...
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FISH Probes and Reagents

We provide a comprehensive menu of Agilent's Sure FISH probes and reagents for rapid identification of a wide range of chromosomal aberrations across the genome As an Agilent Sales Agency we can provide a completet range of probes and reagents to our customers. In areas we are...
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Automatic Staining and Washing

A SciGene Little Dipper Microarray Processor is a programmable, robotic instrument that automates the various hybridization processing steps used with FISH and G-Banding samples. The Little Dipper instrument improves data quality by eliminating sample handling and by controlling...
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Little Dipper for G-Banding

Little Dipper for G-BandingThe SciGene Little Dipper Processor for GTG Banding provides precisely controlled automation staining processing steps used with GTG banding of chromosomes on slides. The robotic system controls staining, wash, agitation, time and buffer temperatures for processing batches of up...
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Little Dipper for FISH

Little Dipper for FISHThe SciGene Little Dipper Processor for FISH automates slide processing for FISH analysis. The robotic system controls staining, wash, agitation, time and buffer temperatures for processing batches of up to 24 slides following optimized protocols. The system eliminates messy...
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